This book focuses on recent advances in research and practical recommendations regarding the use of psychotropic drugs during pregnancy and lactation, two important social and psychological life events for women. In addition to the social context, including the addition of a new family member, many women experience the occurrence or recurrence of psychiatric disorders during the perinatal period. Psychiatric disorders during this period can have negative effects on the fetus, infant and other children in the family, and can result in functional impairment among mothers. The book offers a comprehensive overview of psychopharmacological treatments for nearly all specific psychiatric conditions (e.g. bipolar disorder, panic disorder, obsessive-compulsive disorder) and includes chapters on clinical approaches to treating these disorders. As such, it will appeal to a wide readership, including psychiatrists, obstetricians, gynecologists and pediatricians.
Part I: Introduction To Perinatal Psychopharmacology: Epidemiology of use of psychotropic drugs in pregnant and nursing women. Maternal and infant drug metabolism, and pharmacokinetic changes in psychotropic drugs during pregnancy and the postpartum period. Safety parameters and risk categories used for psychotropic drugs in pregnancy and lactation. General approach to pharmacological treatments during the perinatal period.- Part Ii: Safety Of Psychotropic Drugs During Pregnancy And Lactation: Antidepressants in pregnancy. Antidepressants during lactation. Antipsychotics in pregnancy. Antipsychotics during lactation. Mood stabilizers in pregnancy. Mood stabilizers during lactation. Benzodiazepines and Z-drugs in pregnancy. Benzodiazepines and Z-drugs during lactation.- Part Iii: Pharmacological Management Of Psychiatric Disorders During The Perinatal Period: Major depression. Bipolar disorder. Schizophrenia and related psychoses. Obsessive-compulsive disorder. Anxiety disorders. Posttraumatic stress disorder. Alcohol use disorders. Substance use disorders. Sleep disorders. Eating disorders.
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